HOME

Team

Contact

Prion research Göttingen

 

Project overview

Biomarker

Protecting the food chain from prions (Priority) EU 2009-2013

Development of a blood screening assay for diagnosis of prion diseases in humans (prionscreen) EU 2007-2010

NoE:NeuroNe (Molecular mechanisms of neuronal degeneration: from cell biology to the clinic) EU 2005-2009

NoE:Neuroprion (Prevention, control and management of prion diseases) EU 2004-2009

Early clinical diagnosis of human spongiform encephalopathies by analysis of biological fluids (CJD Markers) EU 2003-2005

Small Interspersed Nuclear Elements (SINEs) als prädisponierender genomischer Faktor und Kofaktor für eine TSE von Tier und Mensch DFG 2002-2005

Cerebrospinal fluid investigations as model to study neurodegenerative disorders in humans (CMPB) DFG 2002-2004

Biomarker development in pron diseases BMBF 2001-2004

Laboratory supported diagnosis of Creutzfeldt-Jakob disease (CJDtest) EU 1998-2001

TSE biobank BMBF 2001-2006

WHO reference center for CSF tests in prion diseases since 2000

 

Bildgebung

Brain imaging as an aid to determine molecular subtype in prion diseases BMBF 2008-2009

Quantitative analysis of MR scans in Creutzfeldt-Jakob disease (QAMRIC) EU 1998-2001

DaTSCAN in subjects with extrapyramidal syndromes GE Healthcare 2009-2012

PDT301-An open-label phase 3 clinical study to assess the striatal uptake of an intravenous solution containing the dopamine transporter radio-ligand, DaTSCAN, in subjects with DLB Amersham Buchler/GE Healthcare 2002-2006

 

Epidemiologie

Netzwerk "Infektionen des Nervensystems"

Nationales Referenzzentrum für transmissible spongiforme Enzephalopathien BMGS/RKI 2006-2010

CJK-Netz (Forschungsnetz zur Verbesserung der Früh- und Differentialdiagnose der CJK und rasch progressiver Demenzen) BMBF 2003-2006

CJD Surveillance in Central and Eastern EU-countries and China (SEEC CJD) EU 2002-2004

Creutzfeldt-Jakob disease: epidemiology, risk factors and diagnostic tests (EUROCJD) 1993-2010

Untersuchungen zur Epidemiologie und Frühdiagnose humaner spongiformer Enzephalopathien BMGS 1996-2006

HTSEs: The neuropathology network (Prionet) EU 2000-2003

 

Therapie

A randomized, double-blind study versus placebo for the evaluation of the efficacy of doxycycline administered by oral route in patients affected by sporadic Creutzfeldt-Jakob disease. BMBF 2009-2013

NoE Neuroprion: The 37 kDa laminin recepor and the membrane bound PrPc as targets in TSE therapy EU 2004-2009

A randomized double blind placebo controlled trial on long term treatment of Galantamine in mild to moderately severe Alzheimer´s disease Janssen-Cilag 2008-2012

Rivastigmine in MS Novartis 2009-2013